PSI CRO

Healthcare

LeadClinicalResearchAssociate

$115–155k ~AI est. United States FULL TIME Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for mid candidates.

The Brief

“Lead Clinical Research Associate at PSI CRO. Skills: Clinical research, Oversight, Compliance. Monitor project timelines. Monitor patient enrollment”

What You'll Achieve.

Ensure high-quality execution; Ensure compliance; Ensure timely delivery; Ensure data integrity; Ensure compliance at site level; Ensure ongoing evaluation of data integrity; Ensure ongoing evaluation of compliance; Ensure subject recruitment targets met; Ensure project timelines met

Industry & Context.

Healthcare
Problems you'll solve

Problem-solving skills

Eligibility Requirements

Ability to travel, Valid driver’s license

What They're Looking For.

Must Have

4 years site monitoring experience, Experience with all visit types, Full working proficiency in English, Proficiency in MS Office applications

Nice to Have

Experience in Oncology preferred, Experience in Radiation Therapy preferred, Experience in CAR-T Therapy preferred, Experience in Gene Therapy preferred, Experience in Nuclear Medicine preferred, Experience in GI preferred

What You'll Do.

Monitor project timelines

Monitor patient enrollment

Monitor data cleaning

Implement corrective measures

Implement preventive measures

Review monitoring visit reports

Ensure reporting compliance

Act as communication line

Lead project team calls

Provide status updates

Provide project-specific training

Prepare training materials

Supervise source data verification

Follow up on data queries

Ensure proper handling of Investigational Product

Ensure use of Investigational Product

Ensure accountability of Investigational Product

Ensure reconciliation of Investigational Product

Ensure return of Investigational Product

Review essential study documents

Supervise reconciliation of study Investigator Site File

Supervise reconciliation of TMF

Ensure data integrity

Ensure compliance at site level

Collaborate with investigator feasibility

Collaborate with site identification

Collaborate with study startup

Manage Monitors in query resolution

Manage Central Monitoring observations

Coordinate safety information flow

Coordinate protocol deviation reporting

Coordinate process deviation reporting

Perform clinical supplies management

Ensure tracking systems updated

Coordinate planning of supervised monitoring visits

Conduct supervised monitoring visits

Manage project team in site contracting

Manage project team in site payments

Ensure ongoing evaluation of data integrity

Ensure ongoing evaluation of compliance

Conduct site audit preparation visits

Participate in site audits

Coordinate resolution of site audit findings

Oversee project team in CAPA development

Oversee project team in CAPA implementation

Coordinate project team in process deviations review

Coordinate project team in process deviations management

Coordinate project team in process deviations reporting

Conduct initial training monitoring visits

Conduct authorization monitoring visits

Act as mentor for new Lead CRAs

Deliver trainings at Investigator Meetings

Deliver presentations at Investigator Meetings

Ensure subject recruitment targets defined

Ensure project timelines defined

Ensure subject recruitment targets communicated

Ensure project timelines communicated

Ensure subject recruitment targets recorded

Ensure project timelines recorded

Ensure subject recruitment targets met

Ensure project timelines met

Ensure accurate information flow with trial sites

Ensure timely information flow with trial sites

Supervise SMAs in document flow

Supervise SMAs in laboratory supplies flow

Support preparation of regulatory submission packages

Support preparation of ethics committee submission packages

How You'll Work.

Team & Collaboration

Cross-functional teams; Study team

Communication Scope

Status updates; Reports

Process & Methodology

Project timelines, Country level projects, Regional level projects

Full Job Description

PSI is a leading Contract Research Organization with more than 25 years in the industry, offering a perfect balance between stability and innovation to both clients and employees. We focus on delivering quality and on-time services across a variety of therapeutic indications. As a Lead Clinical Research Associate, you will hold a leadership role within the study team, overseeing and guiding the clinical team while driving trial activities at a country or regional level. You will ensure high-quality execution, compliance, and timely delivery. You will act as a key point of coordination across cross-functional teams. This role focuses on leadership, mentorship, oversight, and consistency in monitoring practices rather than direct site management, with minimal to no site assignments and a low-travel model, emphasizing remote oversight and overall study quality. Responsibilities: * Monitors project timelines, patient enrollment, data cleaning, and ensuring compliance while implementing respective corrective and preventive measures. * Reviews monitoring visit reports for all visit types and ensures reporting compliance of the Monitors in the region. * Acts as the main communication line between Monitor, Site Management Associate, Regional Project Lead, and/ Project Manager. * Leads project team calls on a country level as well as provides status updates and reports to Regional Lead/ Project Manager. * Provides project-specific training and prepares training materials for the project team under supervision of a Project Manager and Regional Project Lead. * Supervises source data verification and follows up on data queries at site level in the country/region; reviews and manages study risks on a site level. * Ensures proper handling, use, accountability, reconciliation, and return of all Investigational Product(s) and clinical study supplies on a country/region level. * Reviews essential study documents and supervises reconciliation of study Investigator Site File (ISF) / T

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