Guidehouse
HighThroughputExperimentationChemist
Neural analysis suggests this role is
optimal for Mid candidates.
“High Throughput Experimentation Chemist at Guidehouse. Skills: Chemical analysis, HPLC, Mass Spectrometry. Perform chemical reactions. Perform biochemical reactions”
What You'll Achieve.
Standardizing and improving workflows; Deliver quantities to support biological assays; Support medicinal chemistry program; Support advanced testing in animal models; Publication in peer-reviewed journals
Industry & Context.
Devise synthetic routes
Ability to Obtain Public Trust, Federal or DoD Public Trust
What They're Looking For.
Must Have
Master’s degree in chemistry, Minimum TWO (2) years of chemical analysis experience in a laboratory setting, Demonstrated experience with common analytical chemistry techniques such as High-Performance Liquid Chromatography (HPLC) and/ or Mass Spectrometry (MS), Proven ability to document findings as shown through items such as peer reviewed publications, conference presentations/posters, or similar activities, Must be able to obtain and maintain a Federal or DoD Public Trust
Nice to Have
Experience with affinity-chromatography very beneficial, Experience using Microsoft Office Suite, Candidates with an active Public Trust or existing suitability are preferred
What You'll Do.
Perform chemical reactions
Perform biochemical reactions
Perform analytical analyses
Execute chemical synthesis
Optimize small molecule probes
Devise synthetic routes
Synthesize chemical probes
Optimize chemical probes
Formulate chemistry plans
Validate analysis methods
Analyze cell kinetics
Perform bulk-synthesis
Perform organic synthesis
How You'll Work.
Team & Collaboration
Work with staff in identity, purity, and stability analysis; Work with product team
Communication Scope
oral and verbal communication skills
Full Job Description
**_Job Family_ :** Scientist ** _Travel Required_ :** None ** _Clearance Required_ :** Ability to Obtain Public Trust ** _What You Will Do_ :** We are seeking a High Throughput Experimentation Chemist to support reaction optimization and analog synthesis efforts aimed at standardizing and improving these workflows. This is a full-time, on-site opportunity in Rockville, MD. * Perform chemical and biochemical reactions and appropriate analytical analyses. * Collect and review data; analyze and interpret data and results. * Execute chemical synthesis and optimization of small molecule probes for use in biological research. * Purify compounds submitted by chemists. * Devise synthetic routes to target molecules; produce 10-100 member libraries with acceptable purity and deliver quantities to support biological assays. * Synthesize and optimize chemical probes for potency and solubility. * Formulate chemistry plans for the development of soluble, potent, selective small molecule probes of biological function; analyze samples using validated analytical methods for ongoing studies. * Validate analysis methods for the quantification of cell kinetics. * Work with staff in identity, purity, and stability analysis. * Perform bulk-synthesis, purification, and formulation efforts for advanced testing in animal models. * Analyze samples using validated analytical methods for ongoing studies. * Perform organic synthesis in support of the medicinal chemistry program. * Prepare reports to include a summary of the samples (experimental or clinical), the modifications measured, and the results validated; write papers and abstracts detailing research efforts and results for publication in peer-reviewed journals. **_What You Will Need_ :** * Master’s degree in chemistry. * Minimum TWO (2) years of chemical analysis experience in a laboratory setting. * Demonstrated experience with common analytical chemistry techniques such as High-Performance Liquid Chromatography (HPLC) and/ or Mass Sp
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