Takeda
Pharmaceutical
ExecutiveDirector,AIRxProgramLead:Biologics
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“Executive Director, AIRx Program Lead: Biologics at Takeda. Skills: Biologic drug discovery, Program leadership, AI-enabled protein design. Lead biologic drug discovery projects. Manage biologic discovery programs”
What You'll Achieve.
Deliver differentiated medicines; Deliver candidates to clinic; Deliver INDs at pace
Industry & Context.
Go/no-go decisions
What They're Looking For.
Must Have
PhD strongly preferred, 15+ years industry experience, 10+ years scientific leadership, 5+ biologic programs discovery, 3 biologic INDs required, Advanced degree in life sciences
Nice to Have
PhD preferred
What You'll Do.
Lead biologic drug discovery projects
Manage biologic discovery programs
Oversee discovery process
Define program strategy
Articulate program strategy
Evolve program strategy
Build medicine vision
Develop early asset strategy
Evaluate biologic candidates
Prioritize biologic candidates
Lead AI-enabled Design cycles
Lead AI-enabled Test cycles
Drive sequence optimization
Drive affinity maturation
Drive formulation-ready candidate selection
Partner with Clinical teams
Partner with Translational teams
Refine asset strategy
Manage external CDMOs
Represent Takeda externally
Evaluate external opportunities
Deliver programs at pace
Contribute to pipeline strategy
How You'll Work.
Team & Collaboration
Cross-functional teams; Computational scientists; AI/ML specialists; Protein structure experts; Translational biology experts; Protein engineering teams; Biology teams; Translational teams
Communication Scope
Convey complex science; Distill trade-offs
Process & Methodology
Program management
Full Job Description
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s [Privacy Notice](https://jobs.takeda.com/privacynotice) and [Terms of Use](https://www.takeda.com/terms-and-conditions/). I further attest that all information I submit in my employment application is true to the best of my knowledge. ## **Job Description** **About the role:** Takeda Research is constructing a Lab of Tomorrow built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and Discovery Automation & Robotics (DAR). AIRx will have a dedicated group of experienced biologic drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models for large molecule discovery and deliver candidates to the clinic at industry leading speed and success rates. **Objective:** As AIRx Biologics Program Lead, you will own the end-to-end scientific and strategic direction of 2–3 large molecule discovery programs within a unit deliberately designed to remove the structural overhead that slows programs down in large pharma. AI-enabled protein design, internal or externalized wet lab execution, and a direct line to governance: this is the environment elite biologic drug hunters have been waiting for. You will work alongside top computational protein scientists, AI/ML specialists, protein structure and translational biology experts in a model where the science, not the governance calendar, drives the pace and progress. Programs here move because the structure is built for speed. Your job is to make sure that speed produces the right medicines. A proven track record of leading at least 3 bi
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