All Of Our Groups

Healthcare

Director,VaccineFormulationDevelopment

$177–282k Indianapolis, Indiana, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Director candidates.

The Brief

“Director, Vaccine Formulation Development at All Of Our Groups. Skills: Vaccine formulation, Drug product development, Process development, Adjuvanted vaccines. Represent Drug Product team in CM&C teams. Support formulation and process development”

Industry & Context.

Healthcare
Problems you'll solve

Root cause analysis

What They're Looking For.

Must Have

PhD in chemistry, biochemistry, chemical engineering, or related discipline, 10 years of experience in pharmaceutical or biotech industry, Hands-on experience with adjuvanted protein/subunit vaccines, Hands-on experience with bacterial vaccine platforms, Hands-on experience with antigen-display nanoparticles, Experience with preparation of control strategies, Experience with regulatory submissions supporting clinical development and licensure, Demonstrated leadership of vaccine drug product programs, Experience supervising scientists and engineers

Nice to Have

Experience with nanoparticle antigen display / VLP-like platforms, Familiarity with mRNA‑LNP vaccine drug product development, Late-stage vaccine drug product development experience, BLA filing experience, Familiarity with OMV (Outer membrane vesicles) delivery platforms

What You'll Do.

Represent Drug Product team in CM&C teams

Support formulation and process development

Develop adjuvanted protein/subunit vaccines

Develop bacterial vaccine platforms

Develop antigen-display nanoparticle

Build process capabilities for vaccine drug product unit

Support tech transfer of process and formulation

Work closely with synthetic chemistry

Work closely with toxicology

Work closely with ADME groups

Work closely with analytical teams

Work closely with device teams

Lead design of experiments

Lead execution of experiments

Lead interpretation of experiments

Drive definition of formulations

Drive optimization of formulations

Drive definition of processes

Drive optimization of processes

Innovate formulation methodologies

Assess formulation methodologies

Identify research efforts on new vaccine technologies

Spearhead research efforts on new vaccine technologies

Establish proof of concept for technologies

Establish strategic relationships with academia

Establish strategic relationships with start-ups

Accelerate emerging innovation

Access emerging innovation

Drive innovation agenda for the team

Manage input into complementary parts of the project

Administer performance management

How You'll Work.

Team & Collaboration

CM&C teams; Synthetic chemistry groups; Toxicology groups; ADME groups; Analytical teams; Device teams; Academia; Start-ups

Communication Scope

Publications; Presentations

Full Job Description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. **Overview** For more than 150 years, Lilly has been dedicated to meeting the health care needs of people in the United States and around the world. We address these needs primarily by developing innovative medicines—investing a higher percentage of our sales in research and development than any other major pharmaceutical company. The Lilly Bioproduct Research and Development (BR&D) organization is focused on the development and commercialization of parenteral formulations of small molecules and large molecules such as monoclonal antibodies, novel therapeutic proteins and peptides. The organization is also committed to the development of genetic medicines which includes active investments in oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product team is also investing in building new platforms to support complex formulations such as vaccines, lipid nanoparticles, antibody drug conjugates and AAV and other non-viral vector delivery. We are seeking a highly motivated scientific lead with deep, hands-on experience developing through clinical development and commercialization, and a strong emphasis on and complex antigen–adjuvant systems (e.g., aluminum- and emulsion-adjuvanted formulations). Experience with nanoparticle antigen display / VLP-like platforms is highly desirable. Familiarity with mRNA‑LNP vaccine drug product development is a plus but not require

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