Xenon Pharmaceuticals

Biotech

Director,QualityAssurance,GCP

$216–235k Boston, Massachusetts, United States FULL TIME Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Director candidates.

The Brief

“Director, Quality Assurance, GCP at Xenon Pharmaceuticals. Skills: Quality Assurance, GCP, GLP. Lead quality oversight of GLP programs. Manage GLP audit program”

Industry & Context.

Biotech
Problems you'll solve

Root cause analysis

What They're Looking For.

Must Have

Clinical/non-clinical quality background, 5+ years management experience, GLP/GCP/GVP regulations knowledge, Drug development process understanding, Audit experience, CAPA experience, Risk evaluation experience, Strategic thinking ability, Organizational skills, Project team driving ability, Hands on work willingness, Professional communication, Clear communication, Concise communication, Consistent communication, Independent work ability, Collaborative work ability, People management skills, Mentorship skills, Negotiation skills, Conflict resolution skills

Nice to Have

Experience interacting with regulatory inspectorates

What You'll Do.

Lead quality oversight of GLP programs

Manage GLP audit program

Develop annual GLP audit plan

Lead quality oversight of early phase clinical programs

Provide GLP/GCP compliance interpretation

Provide GLP/GCP consultation

Provide GLP/GCP training

Provide root cause analysis

Identify critical quality issues

Escalate critical quality issues

Assist with regulatory inspection preparation

Coordinate regulatory inspections

Maintain cross-functional communications

Collaborate on quality principles

Collaborate on regulatory requirements

Ensure compliance with legislation

Ensure compliance with regulations

Develop GLP/GCP objectives

Propose GLP/GCP objectives

Plan budget proposals

Manage approved budgets

Recruit direct reports

Direct direct reports

Develop direct reports

Evaluate direct reports

How You'll Work.

Team & Collaboration

Cross-functional communications; Internal stakeholders; External stakeholders; Multidisciplinary team

Communication Scope

Interpersonal skills; Excellent communication; Verbal communication; Written communication

Process & Methodology

Project teams, Critical milestones, Timelines, Budgets

Full Job Description

Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE https://www.nasdaq.com/market-activity/stocks/xene) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline https://xenon-pharma.com/pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are important pain targets. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neur

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