Xenon Pharmaceuticals

Biotech

Director,MedicalAffairs(Epilepsy)

$237–263k Boston, Massachusetts, United States; Pawtucket, Rhode Island, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Director candidates.

The Brief

“Director, Medical Affairs (Epilepsy) at Xenon Pharmaceuticals. Skills: Medical Affairs strategy, Epilepsy program support, Cross functional collaboration. Support medical affairs strategy execution. Contribute to medical planning”

Industry & Context.

Biotech
Problems you'll solve

Critical thinking skills

Eligibility Requirements

Travel up to 25%

What They're Looking For.

Must Have

PhD, PharmD, MD education, 7+ years experience, Medical Affairs Management experience, Experience working cross functionally, Experience reviewing scientific publications, Experience participating in promotional material review, Ability to manage multiple projects, Ability to collaborate effectively, Excellent writing skills, Excellent communication skills, Excellent presentation skills, Must be self-motivated, Able to work autonomously

Nice to Have

Neurology or psychiatry background, Neuroscience experience, Epilepsy experience a plus

What You'll Do.

Support medical affairs strategy execution

Contribute to medical planning

Support clinical development activities

Support launch readiness

Engage internal stakeholders

Engage external stakeholders

Translate scientific information

Support medical affairs plans

Maintain understanding of product data

Maintain understanding of disease state

Maintain understanding of clinical landscape

Support internal discussions

Support medical decision making

Contribute to insight gathering

Serve as Medical Affairs partner

Collaborate with Commercial/Marketing

Collaborate with Market Access

Collaborate with Regulatory

Collaborate with Legal/Compliance

Collaborate with Pharmacovigilance

Participate in cross functional forums

Ensure scientific alignment

Ensure compliant communication

Review promotional materials

Review non promotional materials

Ensure scientific accuracy

Ensure compliance with standards

Support scientific engagement

Contribute to advisory boards

Contribute to investigator interactions

Contribute to congress activities

Represent Medical Affairs

Advance understanding of research

Advance understanding of commitment

Conduct all activities

Act in accordance with Company policies

Ensure policies are understood

Ensure policies are followed

How You'll Work.

Team & Collaboration

Cross-functional colleagues; Cross functional forums; Internal stakeholders; External stakeholders; Healthcare professionals; Key opinion leaders; Patient advocacy organizations

Communication Scope

Scientific information; External scientific exchanges; Scientific discussions

Full Job Description

Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE https://www.nasdaq.com/market-activity/stocks/xene) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline https://xenon-pharma.com/pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are important pain targets. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neur

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