Beeline Medicines

Biotechnology

Director,CMCProductDevelopmentBiologics

$220–300k ~AI est. Boston, Massachusetts, United States Remote Friendly
The Brief

“Director, CMC Product Development – Biologics at Beeline Medicines. Skills: CMC Product Development, Biologics Drug Product, Formulation Development, Process Development. Lead end-to-end CMC development. Drive drug product development strategy”

Industry & Context.

Biotechnology

What They're Looking For.

Must Have

10+ years CMC biologics experience, Expertise in drug product formulation, Expertise in fill-finish process development, Experience authoring BLA drug product sections, Experience managing CDMO relationships, Experience with lyophilized formulation, Experience with liquid formulation, Experience with parenteral biologics, Experience with primary packaging compatibility, Experience with extractables/leachable considerations, Working knowledge of biologics drug substance processes, Track record operating in pre-commercial environments, Experience managing cross-functional stakeholder relationships

Nice to Have

Experience with biologics drug substance processes sufficient to partner with Drug Substance teams

What You'll Do.

Lead end-to-end CMC development

Drive drug product development strategy

Ensure integrated delivery of CMC activities

Provide technical oversight of fill-finish operations

Manage process scale-up

Manage process qualification

Manage commercial readiness

Partner with Drug Substance teams

Balance strategic vision with execution

Translate complex science into narratives

Author regulatory documents

Author scientific reports

Author executive presentations

How You'll Work.

Team & Collaboration

Cross-functional teams; External CDMOs; Senior level relationships; Diverse teams; Executive leadership; Non-technical stakeholders; Research teams; Clinical teams; Regulatory teams; Quality teams; External partners; Matrixed organization

Communication Scope

Written communication; Verbal communication; Executive presentations; Regulatory documents; Scientific reports

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