Beeline Medicines

Biotechnology

Director,CMCAnalyticalDevelopmentBiologics

$220–300k ~AI est. Boston, Massachusetts, United States Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Director candidates.

The Brief

“Director, CMC Analytical Development – Biologics at Beeline Medicines. Skills: Analytical Development, Biologics, Regulatory Affairs, CMC. Drive development of analytical methods. Drive qualification of analytical methods”

Industry & Context.

Biotechnology
Problems you'll solve

Deviation investigation; OOS investigation

What They're Looking For.

Must Have

10+ years analytical development experience, Deep technical expertise in biologics analytical methods, Comprehensive knowledge of ICH Q2(R1), Q6B, Q5B/C/E, Experience authoring analytical sections of regulatory submissions, Hands-on experience managing method transfer, Experience designing and executing stability programs, Proven track record operating in pre-commercial environments, Experience managing cross-functional stakeholder relationships, Exceptional ability to translate complex science, Experienced and confident in regulatory agency interactions

Nice to Have

PhD in Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or related, Equivalent work experience

What You'll Do.

Drive development of analytical methods

Drive qualification of analytical methods

Drive validation of analytical methods

Ensure analytical readiness for submissions

Partner with CMC-Drug Substance

Partner with CMC-Drug Product

Partner with Regulatory Affairs

Partner with external CDMOs

Partner with contract analytical labs

Embed robust analytical science

Support internal audits

Support regulatory inspections

Collaborate on platform methods

Collaborate on cross-modality initiatives

Contribute biologics expertise

Mentor analytical scientists

Develop analytical scientists

Contribute to onboarding

Contribute to capability planning

Perform other duties as assigned

How You'll Work.

Team & Collaboration

Cross-functional teams; External partners; Senior level relationships

Communication Scope

Written communication; Verbal communication; Executive presentations; Regulatory documents; Scientific reports

Full Job Description

About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. Job Summary: The Director, CMC Analytical Development – Biologics is a senior scientific leader responsible for driving the development, qualification, and validation of analytical methods supporting biologics drug substance and drug product programs. Reporting to the Executive Director, CMC Analytical Development, this individual is the primary technical authority on biologics characterization and analytical control strategy, ensuring analytical readiness across IND, Phase 1–3, and BLA submission milestones. This role partners closely with CMC-Drug Substance, CMC-Drug Product,, Quality, Regulatory Affairs, and external CDMOs and contract analytical labs to embed robust analytical science into the biologics development pipeline. Work Arrangement support internal audits and regulatory inspections from an analytical perspective. Collaborate with the Analytical Development team on platform methods and cross-modality initiatives, contributing biologics-specific expertise to shared analytical infrastructure. Mentor and develop analytical scientists within the biologics team; contribute to hiring, onboarding, and capability planning as the biologics

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