GSK
biopharma
DirectorClinicalPharmacology
“Director Clinical Pharmacology at GSK. Skills: Model-Informed Drug Development (MIDD), Clinical Pharmacology, Modelling & Simulation, Quantitative Medicine. Lead the end‑to‑end application of MIDD across the drug development lifecycle—from first‑in‑human studies through filing and lifecycle management. Provide clinical pharmacology strategy and evidence‑generation input”
What You'll Achieve.
de risk and accelerate RIIRU programs; faster development; optimal dosing; stronger regulatory positioning; timely approvals; optimal labelling; accelerate patient access to novel therapies; expand therapeutic indications of marketed drugs
Industry & Context.
solve practical problems; sound judgement in complex situations
What They're Looking For.
Must Have
PhD in life sciences or related discipline, MD, or PharmD, with experience in clinical pharmacology, modelling and simulation in pharmaceutical research and development., Significant experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in the pharmaceutical industry., Experience in pharmacometrics and their application to clinical questions in drug development.
Nice to Have
Additional experience in respiratory and immunology would be beneficial., Demonstrated experience of collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results., Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks., Experience working with senior stakeholders in a cross functional environment., Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs., Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design.
What You'll Do.
Lead the end‑to‑end application of MIDD across the drug development lifecycle—from first‑in‑human studies through filing and lifecycle management
Provide clinical pharmacology strategy and evidence‑generation input
Develop and implement robust MIDD & ClinPharm evidence strategies to de risk and accelerate RIIRU programs
Aim for faster development
optimal dosing and stronger regulatory positioning across respiratory
neurodegeneration and emerging areas
Support business development opportunities
Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling
Maintain up to date knowledge of FDA
PMDA and ICH expectations
Embed regulatory considerations and best practices into study design and MIDD strategies
Build network key functions such as AI/ML
computational biology and RWE to embed quantitative approaches into decision making at asset level
Raise GSK’s profile in MIDD
clinical pharmacology
QSP and AI/ML integration through publications
conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogue
How You'll Work.
Team & Collaboration
Build cross‑functional partnerships; Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.); Maintain networks and share best practices in the CPMS community of practice; Build network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level; Demonstrated experience of collaboration in a multi-discipline team; Experience working with senior stakeholders in a cross functional environment
Communication Scope
effective communication
Process & Methodology
prioritizing multiple tasks
Applying for this Director Clinical Pharmacology role?
Most applicants get filtered before a human reads their resume. See if yours makes the cut.
How to Apply on Workday
- Workday has a multi-step form — save your progress after every section.
- "Apply With LinkedIn" can fail or lose data; manual entry is more reliable.
- Watch for the "Submit for Review" final step — hitting "Save" alone does not submit.
- Job requisition numbers are useful when following up with HR by email.
ANONYMOUS · UNFILTERED
What do employees actually say about GSK?
Real rants from real employees. Read before you apply.