Moderna

Biotech

Director,AnalyticalChemistry

$167–301k Cambridge, Massachusetts, United States FULL TIME Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Director candidates.

The Brief

“Director, Analytical Chemistry at Moderna”

Industry & Context.

Biotech
Full Job Description

**The Role:** Moderna is seeking a Director, Analytical Chemistry to provide scientific, strategic, and organizational leadership for discovery-stage analytical chemistry activities supporting mRNA-lipid nanoparticle (LNP) research across a diverse portfolio of nucleic acid medicines. This leader will define and advance analytical strategies that enable rapid design-make-test-learn cycles across novel ionizable lipids, polymers, excipients, payloads, formulations, and delivery systems used in mRNA-LNP therapeutics and vaccines. The successful candidate will serve as a senior analytical partner to medicinal chemistry, computational chemistry, formulation, delivery sciences, platform biology, and selected development functions to accelerate molecular design, analytical decision-making, and candidate progression. The individual will guide analytical approaches spanning small molecules, polymers and lipid characterization, impurity profiling, structure elucidation, orthogonal physicochemical characterization, and fit-for-purpose evaluation of RNA, lipid, and nanoparticle attributes in support of discovery and early development objectives. Building Moderna's technical model for analytical leadership, this role will provide strategic oversight of method development, method qualification and transfer where appropriate, characterization, impurity identification, and analytical control strategy concepts relevant to discovery and translational research. The leader will help define decision-quality analytical packages, ensure alignment of analytical deliverables with program milestones, and provide technical guidance and oversight to both internal teams and external CRO/CDMO partners. This position requires deep expertise in modern analytical chemistry and a strong ability to translate complex data into actionable scientific decisions. The ideal candidate will combine technical depth in separation science, characterization, and structure elucidation with proven leadership expe

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