Keros Therapeutics

biopharma

ContractProcessDevelopmentAssociateII

$0–0k Lexington, Massachusetts, United States
The Brief

“Contract Process Development Associate II at Keros Therapeutics. Skills: Protein purification, Process development, Chromatography, Tangential-flow filtration. Support early stage process development. Act as interface with Research and CMC”

Industry & Context.

biopharma
Problems you'll solve

Troubleshoot process equipment; Data analysis

What They're Looking For.

Must Have

B.S. in Chemical Engineering, Biochemical Engineering, or equivalent, 1-3+ years of experience in biopharma industry, Experience in protein purification, Experience in scale up/down, Experience in process and analytical characterization, Comprehension of downstream processes at small to intermediate scale of cGMP biologics production, Ability to work independently, Ability to work as part of a cross-functional team, Good oral communication skills, Good written communication skills, Ability to adapt to frequent change, Ability to thrive in a dynamic early-stage environment, Communication skills, Organization skills, Knowledge of MS Office, Knowledge of data plotting and graphing software, Ability to communicate results effectively

Nice to Have

Graduate degree (MS and PhD), Hands-on experience with purification unit operations including filtration, chromatography, TFF, UF/DF, Hands-on experience with AKTA, Hands-on experience with UNICORN, Hands-on experience with HPLC systems, Familiarity with automated chromatography platforms (e.g., Cytiva AKTA)

What You'll Do.

Support early stage process development

Act as interface with Research and CMC

Execute and develop downstream processes

Develop downstream purification processes

Provide and analyze data for tech transfer

Perform hands-on execution and optimization

Generate and analyze process and analytical data

Execute routine scale down protein purification

Manage drug substance inventory

Manage protein intermediate inventory

Explore novel purification processes

Perform small-scale studies

Perform pilot scale purification studies

Maintain laboratory notebooks

Maintain digital records

Present data at meetings

Operate process equipment

Troubleshoot process equipment

Perform process scaling

Perform technology transfer

How You'll Work.

Team & Collaboration

Act as interface with Research and CMC organizations; Work within the DSP group; Work with Co-Ops; Present data at process development and CMC department meetings; Work as part of a cross-functional team

Communication Scope

Good oral communication skills; Good written communication skills; Ability to communicate results effectively

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