Vertex
CMCProjectManagement&StrategicOperationsDirector
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optimal for Director candidates.
“CMC Project Management & Strategic Operations Director at Vertex. Skills: Program management, Strategic operations, CMC programs. Lead CMC programs end to end. Drive planning, delivery, adoption”
What You'll Achieve.
Ensure delivery of business value; Ensure activities deliver expected value; Ensure programs delivered on time; Ensure programs delivered within budget; Ensure programs aligned with standards; Ensure programs aligned with objectives; Ensure launch approach meets adoption targets; Ensure launch approach exceeds adoption targets
Industry & Context.
Critical thinking; Systems thinking; Risk-based planning; Scenario analysis; Issue resolution; Risk mitigation; Decision making
What They're Looking For.
Must Have
Bachelor's degree, 10 years of experience
What You'll Do.
Lead CMC programs end to end
Strengthen project management capability
Guide teams toward technical approaches
Converge on scientifically defensible paths
Anticipate downstream implications
Apply systems thinking
Apply risk-based planning
Apply scenario analysis
Identify cross-functional risks
Identify lifecycle risks
Translate uncertainty into scenarios
Translate uncertainty into decision trees
Lead issue resolution efforts
Leverage financial processes
Apply NPV and ROI calculations
Understand competitive landscape
Understand customer needs
Understand industry trends
Drive connections to company goals
Drive connections to functional objectives
Influence departmental collaboration
Guide teams on drug development process
Guide teams on commercialization
Leverage CDMO management principles
Measure progress within projects
Lead program initiation
Lead program planning
Lead program governance
Lead program execution
Lead performance tracking
Oversee stakeholder communication
Oversee resource alignment
Provide direction to workstream leads
Provide direction to project managers
Resolve escalated issues
Support sound decision-making
Ensure programs delivered on time
Ensure programs delivered within budget
Ensure programs aligned with standards
Ensure programs aligned with objectives
Oversee end-to-end program management
Manage progress of workstream leads
Manage contributions of project managers
Ensure activities deliver expected value
Manage contingencies between projects
Monitor interdependencies
Build detailed project plans
Build budgeting models
Build forecasting models
Develop statements of work
Develop stakeholder management plans
Develop guiding principles
Develop project goals
Develop project risks
Develop resource allocation
Develop roles and responsibilities
Secure required resources
Lead required resources
Motivate required resources
Inspire required resources
Establish program governance
Participate in vendor evaluation
Participate in vendor selection
Participate in vendor management
Provide transparency in project progress
Anticipate major risks
Craft feasible solutions
Exercise sound judgement
Make prompt decisions
Manage communication with management
Plan program execution
Execute program project(s)
Coordinate resources across boundaries
Promote adoption of best practices
Develop tools for project management
Develop training methods for project management
Enable successful project management
Ensure project delivery conformance
Recommend improvements to methodologies
Recommend changes to methodologies
Evaluate program costs
Evaluate program benefits
Compare actual results to plan
Compare forecasts to plan
Update plans with accurate information
Report financial information
Report status to leadership
Ensure program solution meets quality requirements
Ensure program solution meets reliability requirements
Ensure launch approach meets adoption targets
Ensure launch approach exceeds adoption targets
Monitor program results deviations
Monitor program performance deviations
Evaluate options for corrective actions
Make recommendations for corrective actions
Implement selected actions
How You'll Work.
Team & Collaboration
Work effectively across functions; Work effectively across teams; Work effectively across organizations
Communication Scope
Synthesize complex information; Clear insights; Clear recommendations; Detailed functional communication
Process & Methodology
Program management, Project management, Risk-based planning, Scenario analysis, Governance, Execution, Performance tracking, Scope management, Timeline management, Budget management, Risk management, Issue management, Dependency management, Stakeholder communication, Resource alignment, Workstream management, Decision making, Project lifecycle, Contingency management, Interdependency monitoring, Synergy monitoring, Project planning, Budgeting, Forecasting, Resource planning, Statement of work development, Stakeholder management, Guiding principles, Project goals, Resource allocation, Roles and responsibilities, Vendor management, Risk mitigation, Issue resolution, Communication management, Cross-functional planning, Project execution, Methodology training, Best practice adoption, Project delivery, Cost evaluation, Benefit evaluation, Status reporting, Quality assurance, Reliability assurance, Launch planning, Corrective actions
Full Job Description
**Job Description** **General Summary:** The Project Management and Strategic Operations Director leads large-scale, high-value CMC programs end to end, setting a high standard for decision quality, governance, risk management, and execution. This role combines deep program management discipline, technical and business judgment, and strong stakeholder leadership to drive planning, delivery, adoption, and continuous improvement across the function. The Director also coaches teams, strengthens project management capability, and serves as a trusted partner on complex internal and external programs. * **Scientific Knowledge/CMC Expertise** * Demonstrates strong command of planning and executing CMC programs to guide teams toward phase-appropriate, risk-based technical approaches. * Recognizes as a go-to partner for scenario planning of complex CMC topics and understands impacts/trade-offs of technical changes across CMC disciplines. * Helps teams converge on scientifically defensible paths under uncertainty in preparation for governance decision making. * Anticipates downstream clinical, regulatory and manufacturability implications relative to the CMC strategy. * **Program/Project Management Expertise** * Leads complex technical decision-making by applying systems thinking, risk-based planning, and scenario analysis. Anticipates ambiguity and structures work to maintain momentum and optionality. Observable behaviors: * Proactively identifies cross-functional and lifecycle risks. * Translates uncertainty into executable scenarios and decision trees. * Leads issue resolution efforts spanning multiple functions and sites. * **Business Acumen** * Leverages understanding of financial processes (e.g. LRP, AOP, BvA), company business statements, NPV and ROI calculations and applies to projects. Understands competitive landscape, customer needs and industry trends in context of projects/programs. * Drives connections between daily personal and project/program team actions with
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