AssociateScientist-ProcessDevelopment

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. We are seeking a highly motivated Principal Engineer to join the Downstream Process Development team. The successful candidate will lead development and optimization of downstream purification processes supporting viral vector programs from research through preclinical development. The ideal candidate will possess deep technical expertise in downstream purification technologies including ultracentrifugation, chromatography, and tangential flow filtration (TFF), with demonstrated experience driving process development strategies, platform development initiatives, technology implementation, and multi-functional collaboration. This role requires strong scientific leadership, hands-on technical capability, and the ability to independently lead complex purification development activities in a fast-paced environment. **Key Responsibilities** * Lead development, optimization, and scale-up of downstream purification workflows for viral vectors. * Design and implement purification strategieusingng Iodixanol and CsCl density gradient ultracentrifugation, affinity chromatography, ion-exchange chromatography (AEX/CEX), membrane chromatography, and polishing operations. * Lead AKTA-based chromatography workflow development and process intensification initiatives. * Develop scalable downstream platform approaches to support rapid material generation and process consistency across programs. * Independently design experiments, analyze data, i