Regeneron
AssociateScientist,NovelOligonucleotideDeliveryPlatforms
Neural analysis suggests this role is
optimal for Mid+ candidates.
“Associate Scientist, Novel Oligonucleotide Delivery Platforms at Regeneron. Skills: Oligonucleotide delivery, Genetic medicines, Protein characterization. Maintain bacterial cells. Manipulate bacterial cells”
Industry & Context.
Troubleshoot logistical hurdles; Troubleshoot technical hurdles
What They're Looking For.
Must Have
BS/MS in molecular biology, BS/MS in biochemistry, BS/MS in bioengineering, BS/MS in related field
Nice to Have
Cloning experience, Bacterial-based expression systems experience, Self-assembled VLPs experience, Aseptic technique experience, Mammalian cell culture experience, Chromatography experience, AKTA Pure operation experience, SDS-PAGE/CE experience
What You'll Do.
Maintain bacterial cells
Manipulate bacterial cells
Maintain mammalian cells
Manipulate mammalian cells
Perform reporter assays
Characterize proteins
How You'll Work.
Team & Collaboration
Collaborate with team members; Collaborate with other groups
Full Job Description
We are seeking a highly motivated associate scientist to join the Non-Viral Delivery Technologies group within Regeneron Genetic Medicines. You will support production, purification, and characterization of proteins and larger macromolecular protein-based nanocarriers to be used in next-generation delivery technology development, further expanding the company’s growing genetic medicines portfolio. **In this role, a typical day might include the following:** * Maintenance and manipulation of bacterial and mammalian cells for protein expression * Designing and cloning constructs into appropriate expression vectors * Operation of AKTA systems for small scale purification by liquid chromatography-based techniques (e.g. affinity, ion exchange, size exclusion) * In vitro reporter assays with adherent and suspension cell lines or primary cells * Characterization of proteins (e.g. SDS-PAGE, SE-UPLC, CE, DLS) * Working collaboratively with other team members and groups around the company **This role might be for you if you:** * Enjoy working in a fast-paced environment with rapid hypothesis generation and testing * Can troubleshoot through logistical and technical hurdles as they arise * Can work independently and show initiative to continually improve protocols and processes * Can tolerate failure, ambiguity, data-driven pivots on changing priorities and project direction **** **To be considered for this role, you must have:** * A BS/MS in molecular biology, biochemistry, bioengineering, or related fiel * Previous experience in cloning, bacterial-based expression systems, self-assembled VLPs are a plus. * Experience with aseptic technique used in mammalian cell culture, chromatography, running an AKTA Pure, and SDS-PAGE/CE are distinct advantages. * To be successful in this role, you need to work collaboratively, have attention to detail, and be organized. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive cult
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