Strand Therapeutics
biotechnology
AssociateScientistI,NanoparticleProcessDevelopment
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“Associate Scientist I, Nanoparticle Process Development at Strand Therapeutics. Skills: Nanoparticle Process Development, LNPs, scale-up. Execute experiments related to LNP mixing. Execute experiments related to downstream purification/filtration”
What You'll Achieve.
improve the process; emphasis on scale-up, tech-transfer and stability
Industry & Context.
What They're Looking For.
Must Have
B. S. or Advanced Degree with at least 1-2 year of relevant experience, Chemical Engineering, Bioengineering or similar, Experience with LNPs required, collaboration and inter-personal skills, Ability to multi-task and prioritize to meet important deadlines
Nice to Have
nucleic acid payloads highly preferred, Experience with TFF required with emphasis on LNPs preferred, Experience with QbD principles, scale up efforts and JMP DOE preferred, Experience with various mixing geometries as well large scale LNP production preferred
What You'll Do.
Execute experiments related to LNP mixing
Execute experiments related to downstream purification/filtration
Contribute to development of a robust formulation process
Contribute to thorough characterization of LNPs
Collaborating with internal stakeholders on developing new methods
Coordination with other team members to support research activities
How You'll Work.
Team & Collaboration
work in a matrix-based environment; Coordination with other team members; collaborating with internal stakeholders; team-focused small company environment; working together to meet Strand’s goals
Full Job Description
Company Overview: Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients. Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits. Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts. Become the next standout single strand! Job Summary: Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company. We are looking for a highly motivated and innovative candidate for the role of Associate Scientist I of Nanoparticle Process Development. This individual will support in production and scale up of LNPs with nucleic acid payload. Reporting to the Principal Scientist of Nanoparticle Process Development, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a deep scientific knowledge. Primary Responsibilities: Execute experiments related to LNP mixing and downstream purification/filtration to improve the process. Contribute to development of a robust formulation process with emphasis
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