Vertex

Biotechnology

AssociateDirector,R&DQualityRegulatory&RiskIntegration

$161–241k Boston, Massachusetts, United States FULL TIME Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Director candidates.

The Brief

“Associate Director, R&D Quality Regulatory & Risk Integration at Vertex. Skills: Regulatory Intelligence, Quality Risk Management, Governance. Establish Regulatory Intelligence & Surveillance process. Implement Regulatory Intelligence & Surveillance process”

Industry & Context.

Biotechnology
Problems you'll solve

Root cause analysis; Risk assessment

What They're Looking For.

Must Have

Bachelor's degree in Life Sciences, 8+ years of experience in Quality, Regulatory Affairs, Regulatory Intelligence, Quality Risk Management, Clinical Quality, or related GxP functions, knowledge of GxP regulations, knowledge of inspection readiness principles, knowledge of quality management systems, Experience supporting governance forums, Experience participating in cross-functional initiatives, Demonstrated ability to translate complex regulatory information into actionable business or quality insights, stakeholder engagement skills, facilitation skills, communication skills, Experience influencing across matrixed organizations

Nice to Have

Advanced degree (MS, PharmD, PhD, MBA, etc.), Experience with Regulatory Intelligence & Surveillance programs, Experience with governance, Experience with Quality Risk Management methodologies, Experience with risk governance, Familiarity with ICH E6(R3), Familiarity with inspection trends, Familiarity with emerging global regulatory expectations, Experience supporting enterprise transformation initiatives, Experience supporting cross-functional transformation initiatives

What You'll Do.

Establish Regulatory Intelligence & Surveillance process

Implement Regulatory Intelligence & Surveillance process

Mature Regulatory Intelligence & Surveillance process

Ensure alignment with enterprise RI&S processes

Define RI&S intake pathways

Define RI&S triage pathways

Define RI&S escalation pathways

Define RI&S impact assessment pathways

Define RI&S governance integration pathways

Develop processes for identifying regulatory intelligence

Develop processes for evaluating regulatory intelligence

Develop processes for operationalizing regulatory intelligence

Maintain oversight of regulatory intelligence governance

Translate external regulatory intelligence into insights

Translate external regulatory intelligence into recommendations

Facilitate risk-based evaluation of regulatory expectations

Integrate regulatory intelligence into risk management

Integrate regulatory intelligence into governance forums

Partner with stakeholders to assess risks

Partner with stakeholders to escalate risks

Support development of mitigation strategies

Support development of readiness strategies

Serve as Quality System Owner for RI&S

Represent RI&S within RDQ governance forums

Develop executive-level summaries

Develop trend analyses

Develop risk insights for leadership

Support integration of RI&S into RDQ governance

Support integration of RI&S into RDQ operating model

Serve as RDQ Regulatory Intelligence Champion

Build partnerships with Quality

Build partnerships with Clinical Development

Build partnerships with Regulatory Affairs

Build partnerships with Global Quality Systems

Build partnerships with Inspection Readiness

Partner with business functions to support interpretation

Partner with business functions to support operationalization

Facilitate alignment between intelligence activities and priorities

Provide quality support to Regulatory Affairs

Monitor inspection trends

Assess inspection trends

Monitor enforcement actions

Assess enforcement actions

Monitor health authority focus areas

Assess health authority focus areas

Monitor evolving industry expectations

Assess evolving industry expectations

Support proactive inspection readiness efforts

Identify emerging themes impacting compliance

Identify systemic trends impacting compliance

Support Regulatory Affairs in preparing for inspections

How You'll Work.

Team & Collaboration

Cross-functional stakeholders; Enterprise RI&S forums; Quality System Owners; Regulatory Affairs; Global Quality Systems; Inspection Readiness

Communication Scope

Executive summaries; Trend analysis; Risk insights

Process & Methodology

Governance, Process improvement

Full Job Description

**Job Description** **General Position Summary** The Associate Director, R&D Quality Regulatory & Risk Integration is responsible for establishing, implementing, and maturing the R&D Quality Regulatory Intelligence & Surveillance (RI&S) process within RDQ and serving as the main quality point of contact for Regulatory Affairs. This role serves as the strategic integration point between external regulatory intelligence, proactive quality risk management, governance processes, and inspection readiness activities across R&D Quality. The role partners closely with Global Regulatory Intelligence & Surveillance functions, RDQ leadership, Quality System Owners, Regulatory Affairs, and other cross-functional stakeholders to ensure emerging regulatory expectations, inspection trends, enforcement actions, and industry signals are proactively translated into actionable RDQ risk, governance, and operational activities. This individual will serve as the RDQ Regulatory Intelligence Champion (RIC) within enterprise Regulatory Intelligence forums and Centers of Excellence and will represent the Regulatory Intelligence Quality System within RDQ governance forums including the RDQ Quality Leadership Team (QLT), Quality Management Review (QMR), Monthly Risk Review Forum, and operational governance meetings. The Associate Director will serve as a quality business partner to Regulatory Affairs functions and be the resource for quality consults, process improvement initiatives, quality events, and inspection readiness activities. This position sits within the R&D Governance & Risk Management organization and plays a key role in advancing proactive, risk-based governance and inspection readiness capabilities across RDQ. # Key Responsibilities ## Regulatory Intelligence & Surveillance Process Leadership * Establish, implement, and continuously mature the RDQ Regulatory Intelligence & Surveillance process and operating model * Ensure alignment and connectivity with enterprise/global Regulat

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