Relation

TechBio

AssociateDirector/DirectorMedicinalChemistry

London, United Kingdom FULL TIME Remote Friendly
The Brief

“Associate Director/Director Medicinal Chemistry at Relation. Skills: medicinal chemistry strategy, small molecule drug discovery, lead optimisation, development candidate selection, structure-based design, multiprofile optimisation, computational and data-driven methods. Lead medicinal chemistry strategy across discovery programmes. Lead medicinal chemistry activities from hit identification through to development candidate selection”

What You'll Achieve.

discover transformational medicines; understand human biology in unprecedented ways; discover therapies to treat some of life’s most devastating diseases; drive disease understanding, from cause to cure; translate insight into impact; help define how medicines are discovered; deliver meaningful impact for patients; drive scientific and portfolio impact; achieve key milestones and value inflection points; deliver high-quality molecules with balanced potency, selectivity and developability; accelerate programme delivery; deliver high-quality scientific outcomes; progress of molecules into development; strive to deliver meaningful outcomes

Industry & Context.

TechBio
Problems you'll solve

solve complex scientific challenges; scientifically rigorous

What They're Looking For.

Must Have

PhD in medicinal chemistry, synthetic organic chemistry, or a related scientific discipline or equivalent experience in industrial drug discovery, Significant experience leading medicinal chemistry programmes within biotech, pharmaceutical or CRO environments, Demonstrated success progressing drug discovery programmes through lead optimisation to development candidate selection, with clear impact on project strategy and delivery, Deep expertise in modern medicinal chemistry approaches, including structure-based drug design, multiparameter optimisation, and the application of computational and data-driven methods to molecule design, Experience building and managing productive collaborations with CROs and external partners to deliver high-quality scientific outcomes, record of scientific achievement and innovation, evidenced through publications, patents, presentations and progression of molecules into development, Passion for small molecule drug discovery, with curiosity for emerging technologies and enthusiasm for integrating computational approaches with experimental science, Excellent communication, influencing and interpersonal skills, with the ability to thrive in a collaborative, cross-functional, matrixed environment, Highly motivated, scientifically rigorous, and comfortable operating in a fast-paced, evolving biotech setting

Nice to Have

Working with modalities such as peptides, ADCs, oligonucleotides or targeted delivery approaches

What You'll Do.

Lead medicinal chemistry strategy across discovery programmes

Lead medicinal chemistry activities from hit identification through to development candidate selection

Design and optimise novel chemical matter

Partner closely with cross-functional colleagues

Lead and manage external collaborations and CRO partnerships

Represent medicinal chemistry in project teams

governance forums and portfolio reviews

Contribute to the growth and evolution of Relation’s discovery capabilities

Champion Relation’s collaborative

ambitious and science-driven culture

How You'll Work.

Team & Collaboration

work in highly interdisciplinary teams; partner closely with colleagues across Discovery and beyond; work in a collaborative, cross-functional, matrixed environment; operate in a matrixed, interdisciplinary environment; partner with colleagues across multiple teams and projects; contributing your expertise while aligning to shared company priorities

Communication Scope

Excellent communication; influencing; interpersonal skills; communicating scientific strategy, progress, opportunities and risks clearly to senior stakeholders; Communicate openly and directly; give and receive feedback constructively; handle challenging conversations with respect

Process & Methodology

managing productive collaborations with CROs and external partners, ensuring effective execution, clear prioritisation and delivery against timelines, budgets and project goals

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